Specialized Pro-resolving Mediators (SPMs), a Novel Nutritional Approach to...

This research review on Specialized Pro-resolving Mediators (SPMs) covers a novel nutritional approach to resolve inflammation. Acute and chronic inflammation is a widespread common...
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Inflammation: Targeting Clinical Patients: Stephen McClave, MD

ASPEN 2015 Inflammation – Targeting Clinical Patients for Improved Care and Outcome: Stephen McClave, MD In this video, Stephen McClave, MD, Professor and Director...
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ASPEN Closing & Summary on Inflammation, Robert Martindale, MD,...

In this video, Robert Martindale, MD, PhD, Professor and Chief of General Surgery in Portland, Oregon brings it all home in his closing summary...
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ASPEN 2015 – Closing Comments and Q&A on Inflammation,...

ASPEN 2015 on Inflammation – Closing Comments and Q&A, Robert Martindale, MD In this video, Robert Martindale, MD, PhD, Professor and Chief of General...
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Resolvins and Protectins: Chemistry and Biology

Inflammation is improved in patients undergoing nutritional therapy where resolvins and protectins are introduced. Studies have elucidated that the ingestion of fish oils may...
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Aspirin-Triggered Resolvin D1 Prevents Surgery-Induced Cognitive Decline

Hospitalization for major surgery or critical illness often associates with cognitive decline. Inflammation and dysregulation of the innate immune system can exert broad effects...
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Resolvins, Specialized Proresolving Lipid Mediators, and Their Potential Roles...

Acute inflammation is healthy for the body, but when inflammation becomes chronic, is can damage tissues and be detrimental to health. The resolution of...
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Pro-Resolving Lipid Mediators and Diabetic Wound Healing

Diabetic patients often suffer from defective wound healing that is associated with both type 1 and type 2 diabetes. Unresolved inflammation and poor wound...
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Immunoresolving Lipid Mediators and Resolution of Inflammation in Aging

Unresolved inflammation is associated with several widely recurrent aging-associated diseases such as arthritis, periodontitis, metabolic disorders, atherosclerosis, and neurodegeneration. Endogenous mechanisms that curtail excessive...
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Resolvin D1 and Resolvin D2 Govern Local Inflammatory Tone...

The unprecedented increase in the prevalence of obesity and obesity-related disorders is causally linked to a chronic state of low-grade inflammation in adipose tissue....
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Novel N-3 Immunoresolvents: Structures and Actions

Resolution of inflammation is now held to be an active process where autacoids promote homeostasis. This downloadable article discusses the role of DPA and...
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Humanized Nano Pro-Resolving Medicines Mimic Inflammation-Resolution and Enhance Wound...

This downloadable article is on the findings from a study on endogenous microparticles. Endogenous microparticles (MPs) were systematically profiled during the time course of...
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Resolvin D2 is a Potent Regulator of Leukocytes and...

This downloadable article builds upon a growing body of evidence indicating that resolution of acute inflammation is an active process. Resolvins are a new...
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Infection Regulates Pro-Resolving Mediators that Lower Antibiotic Requirements

This downloadable article discusses the relationship between bacterial infections and acute inflammation. Underlying mechanisms for how bacterial infections contribute to active resolution of acute...
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Resolvin D1 and Its Aspirin-Triggered Epimer AT-Rvd1 Promote the...

Resolvins are generated from omega-3 fatty acids during inflammatory responses in the lung. These natural mediators interact with specific receptors to decrease lung inflammation...
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A Novel Anti-Inflammatory and Pro-Resolving Role for Resolvin D1...

Abstract INTRODUCTION: Cigarette smoke is a profound pro-inflammatory stimulus that contributes to acute lung injuries and to chronic lung disease including COPD (emphysema and...
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Resolvin E1, an Endogenous Lipid Mediator Derived From Omega-3...

This downloadable article from inflammation resolution expert Dr. Charles Serhan and colleagues discusses one particular lipid mediator called Resolvin E1 (RvE1; 5S,12R,18R-trihydroxyeicosapentaenoic acid). It...
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Resolution of Inflammation: State of The Art, Definitions and...

This downloadable publication came out of a focus meeting on Controlling Acute Inflammation, held in London, April 27-28, 2006, organized by D.W. Gilroy and...
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