At ASPEN 2016, MHICN sat down with Dr. Philip Calder, Professor of Nutritional Immunology at the University of Southampton in Southampton, UK. The conversation was about the omega-3 fatty acids, EPA and DHA, and specialized pro-resolving mediators (SPMs).

In this fourth video, Dr. Calder explains how he became interested in SPMs. He has long been interested in the biological activity of omega-3 fatty acids and how it relates to the development of chronic inflammatory diseases. He is very excited about the role of EPA and DHA pro-resolving mediators and is interested in finding out more about inflammation resolution.

The sources of production of SPMs are EPA and DHA omega-3 fatty acids. DPA (omega-6 and omega-3) is also a source of SPMs, as is arachidonic acid, which produces the lipoxin family of mediators.

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