Studies were sought if they were observational cohort, case cohort studies, or prospective nested case control studies; had reported on at least one of the sex hormones as exposures: SHBG, total testosterone, bioavailable testosterone, total estradiol and bioavailable estradiol; and had assessed associations with risk of T2D in women (pre, peri or postmenopausal)

Objectives

  •  To investigate the association between sex hormones and type 2 dabetes (T2D) in postmenopausal women using the data from a large population-based prospective study
  • To systematically review and meta-analyze studies evaluating prospectively the association between sex hormones and T2D in women

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